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Table 2 Individualized order of the anti-seizure medication administered

From: Stiripentol for the treatment of refractory status epilepticus

Patient

Anti-seizure medication

1

BZD → LEV → LCM → VPA → STP

2

(ZNS, PER, LEV, VPA, CZP) → LZP → LEV → VPA → MDZ/ Esketamine → Cortisone → THP → CZP → LCM → PER → ZNS → STP

3

(LTG, LEV, VPA) → LZP → LEV → VPA → Propofol → MDZ → LCM → STP

4

(LEV) → LZP → LEV → LCM → VPA → BRV → STP

5

(LEV, ZNS, LCM) → LZP → LEV → VPA → LCM → Propofol → ZNS → MDZ → THP → TPM → PER → Cortisone → Esketamine → STP

6

(LEV) → LZP → LEV → VPA → LCM → STP

7

(LTG) → LZP → LEV → LCM → TPM → STP

8

(CLB, LCM, GBP, TPM) → LEV → STP

9

(LEV) → LZP → VPA → LCM → Propofol → PER → CLB → STP

10

(LEV, VPA, ESL, PER) → CLB → BRV → STP

11

BZD → LEV → VPA → LZP → LCM → TPM → STP

12

(LCM, LEV, VPA) → LZP → TPM → PER → Propofol → ESL → Cortisone → THP → Isoflurane → PHT → STP

13

(LEV, TPM, LCM, CLB) → LZP → MDZ/ Esketamine → Cortison → PB → TPM → STP

14

(LTG, PB, PER, BRV) → LZP → LEV → VPA → Propofol → MDZ/ Esketamine → TPM → THP → Cortisone → STP

15

(VPA, LEV, PER) → LZP → STP

16

(LEV, LTG) → LZP → LEV → LCM → PER → TPM → CBZ → Propofol → VPA → MDZ/ Esketamine → STP

17

BZD → LEV → VPA → Propofol → LCM → LZP → THP → TPM → STP

18

(VPA, LEV) → LZP → LEV → VPA → PER → LCM → STP

19

(VPA) → LZP → VPA → LEV → STP

20

(LEV) → LZP → LEV → LCM → TPM → STP

21

LZP → LEV → LCM → PER → STP

22

(LEV, VPA, LCM, PHT) → BRV → VPA → MDZ/ Esketamine → CLB → STP

23

(BRV, LCM) → LZP → VPA → Propofol → MDZ/ Esketamine → Cortisone → STP

24

LZP → LEV → LCM → Cortisone → TPM → BRV → Propofol → MDZ → VPA → STP

25

MDZ → LEV → LCM → BRV → VPA → STP

  1. BZD: Benzodiazepine, BRV: Brivaracetam, CLB: Clobazam, CZP: Clonazepam, LCM: Lacosamide, LEV: Levetiracetam, LTG: Lamotrigine, LZP: Lorazepam, MDZ: Midazolam, PB: Phenobarbital, PER: Perampanel, PHT: Phenytoin, STP: Stiripentol, TPM: Topiramate, VPA: Valproic acid, ZNS: Zonisamide