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Table 2 Outcomes

From: Association of high-density lipoprotein cholesterol with reduced intracranial haemorrhage and favourable functional outcome after thrombectomy for ischaemic stroke: a propensity-matched analysis

 

Patients receiving thrombectomy (n = 807)

Low HDL-C (< 1.15mmol/L) (n = 386)

High HDL-C (≥ 1.15 mmol/L) (n = 369)

p-value

Procedural Outcomes (n, %)

   

0.887

Thrombectomy frustrate

89, 11.02

41, 10.62

39, 10.57

 

mTICI (n, %)

    

  0

70, 8.67

30, 7.77

32, 8.67

 

  1

8, 0.99

4, 1.04

4, 1.08

 

  2a

40, 4.96

25, 6.48

13, 3.52

 

  2b

276, 34.20

129, 33.42

131, 35.50

 

  2c, 3

417, 51.67

198, 51.30

189, 51.22

 

Post-interventional ICH (n, %)

   

0.000

Any post-interventional ICH

337, 41.76

192, 49.74

123, 33.33

 

Haemorrhagic transformation (HI1, HI2)

211, 26.15

122, 31.61

78, 21.14

 

Intracranial bleeding (PH1, PH2)

85, 10.53

47, 12.18

33, 8.94

 

Subarachnoid haemorrhage (Class 3c)

118, 14.62

68, 17.62

41, 11.11

 

Symptomatic haemorrhage

17, 2.11

10, 2.59

5, 1.36

 

Clinical Outcomes (n, %)

NIHSS at discharge (median, [IQR])

7 [2, 17]

9 [2, 19]

5, [1, 14]

0.001

mRS at discharge (median [IQR])

4 [2, 5]

4 [2, 5]

3 [2, 5]

0.002

mRS at 90 days (median [IQR])

3 [2, 6]

4 [2, 6]

3 [1, 4]

0.000

mRS (0–2) at 90 days (n, %)

290, 35.94

121, 31.35

158, 47.82

0.002

  1. Class 3c, subarachnoid haemorrhage according to Heidelberg Bleeding Classification; HDL-C, high-density lipoprotein cholesterol; HI, haemorrhagic infarction according to Heidelberg bleeding classification; ICH, intracranial haemorrhage; IQR, interquartile range; mTICI, modified treatment in cerebral infarction score; NIHSS, National Institutes of Health Stroke Scale; mRS, modified Rankin scale; PH, parenchymal haematoma according to Heidelberg Bleeding Classification