Fig. 1
From: Diagnosis, pathomechanisms and therapy of cerebral amyloid angiopathy-related inflammation (CAA-ri)
The pathomechanisms behind CAA-ri. In CAA-ri, anti-Aβ autoantibodies produced in the CSF of affected patients cause various autoinflammatory processes. Due to peri- and intravascular inflammation following microglial activation, vasogenic edemas comparable to iatrogenic ARIA-E are favored. CAA-ri also increases the risk for cerebral micro- as well as macrobleeds. Figure created with BioRender.com