Table 2 In-hospital outcomes
TNK (n = 138) | rt-PA (n = 138) | P Value | |
|---|---|---|---|
Procedure times, min; median (IQR) | |||
Door-to-needle | 27 (19–39) | 34 (25–62) | 0.011 |
Door-to-imaging | 15 (9–21) | 17 (13–22) | 0.12 |
Imaging-to-needle | 11 (9–16) | 17 (10–31) | 0.037 |
Door-to-groin | 65 (57–80) | 72 (64–106) | 0.17 |
Door-to-recanalization | 97 (80–127) | 111 (88–152) | 0.25 |
Door-to needle within 30 min; n (%) | 73 (53%) | 55 (40%) | 0.030 |
Procedure times for evident strokes (NIHSS > 4, time window ≤ 4.5h), min; median (IQR) | |||
Door-to-needle | 25 (17–46) | 31 (23–50) | 0.018 |
Door-to-imaging | 14 (9–17) | 15 (11–20) | 0.21 |
Imaging-to-needle | 11 (7–23) | 14 (8–24) | 0.041 |
Door-to-groin | 60 (55–77) | 71 (64–105) | 0.05 |
Door-to-recanalization | 90 (78–104) | 106 (97–148) | 0.15 |
Door-to needle within 30 min; n (%) | 36 (67%) | 31 (48%) | 0.046 |
Clinical in-hospital outcomes during the first 72h | |||
Early major NIHSS improvement (≥ 4 within 72h); n (%) | 49 (36%) | 54 (39%) | 0.53 |
Early major NIHSS deterioration (≥ 4 by day 1 or 3)*; n (%) | 16 (12%) | 21 (15%) | 0.38 |
Early recanalization pre-EVT; n (%) | 3 (10%) | 1 (3%) | 0.27 |
Cancellation of IVT; n (%) | 0 (0%) | 2 (1%) | 0.16 |
Radiological outcomes | |||
mTICI after EVT**; n (%) | 0.87 | ||
mTICI 3 | 20 (65%) | 21 (64%) | |
mTICI 2c | 2 (7%) | 3 (9%) | |
mTICI 2b | 5 (16%) | 6 (18%) | |
mTICI 2a | 1 (3%) | 0 (0%) | |
mTICI 0 | 3 (10%) | 3 (9%) | |
Successful reperfusion (mTICI 2b-3); n (%) | 27 (87%) | 30 (91%) | 0.63 |