Table 1 Patient characteristics and demographics

Age, mean (± SD)

66.8 (12.4)

67.1 (13.2)

66.1 (10.8)

Sex, female, n (%)

34 (40.5)

23 (42.6)

11 (36.7)

Hypertension, n (%)

55 (65.5)

34 (62.9)

21 (70)

Diabetes, n (%)

16 (19.1)

10 (18.5)

6 (20.0)

Hyperlipidemia, n (%)

36 (42.9)

21 (38.9)

15 (50.0)

Atrial fibrillation, n (%)

26 (30.9)

17 (31.5)

9 (30.0)

History of smoking, n (%)

19 (22.6)

12 (22.2)

7 (23.3)

TOAST Classification (Adams 1993)

Large artery atherosclerosis, n (%)

45 (53.6)

25 (46.3)

20 (66.7)

Cardioembolic stroke, n (%)

26 (30.9)

17 (31.5)

9 (30.0)

Small vessel occlusion, n (%)

7 (8.3)

6 (11.1)

1 (3.3)

Other, n (%)

2 (2.4)

2 (3.7)

0 (0)

Unknown, n (%)

4 (4.8)

4 (7.4)

0 (0)

NIHSS at admission, median (IQR)

2 (1–4)

2.5 (1–4)

1 (0–4)

ARWMC score, median (IQR)

5 (2-9.5)

5 (2–9)

4 (2–10)

DWI lesion volume at baseline, median (IQR)

4.8 (1.0-13.5)

1.9 (0.6–7.1)

9.7 (5.1–25.1)

Thrombolysis, n (%)

33 (39.3)

21 (38.9)

12 (40)

Modified Rankin Score T3, median (IQR)

1 (1–2)

1 (1–2)

1 (0–2)

Barthel Index T3, median (IQR)

100 (100–100)

100 (100–100)

100 (100–100)

Medication with antidepressants T2, n (%)

4 (4.8)

3 (5.6)

1 (3.3)

Medication with antidepressants at any timepoint (T2, T3, T4), n (%)

7 (8.3)

6 (11.1)

1 (3.3)