Table 2 Assessment of primary and secondary outcome parameters based on lesion location assessed at 90 days post-stroke. *Effect sizes are reported as Cohen’s d for continuous variables and odds ratios (OR) with 95% confidence intervals for binary variables
From: Neuropsychiatric changes following striatal stroke– results from the observational PostPsyDis study
Striatal (N = 54) | Non-striatal (N = 30) | p-value | Effect Size* | 95% CI | ||
|---|---|---|---|---|---|---|
Primary study endpoints | GDS-30 total score, median (IQR) | 5.9 (3–9) | 3 (2–6) | 0.057 | 0.39 | −0.07–0.83 |
Depression yes/no, n (%) | 12 (22.2) | 3 (10) | 0.16 | 0.39 | 0.1–1.5 | |
PTSS-10 total score, median (IQR) | 10 (2–16) | 6 (3–10) | 0.25 | 0.19 | −0.26 to 0.64 | |
PTSD yes/no, n (%) | 9 (16.7) | 4 (13.3) | 0.17 | 0.77 | 0.22–2.7 | |
Secondary study endpoints | SF-12 PC score, median (IQR) | 47.5 (37.3) | 53 (41.1–55.9) | 0.16 | −0.23 | −0.76 to 0.29 |
SF-12 MCS score, median (IQR) | 55.2 (46.0–59.4) | 55.2 (52.4–59.3) | 0.52 | −0.25 | −0.76 to 0.26 | |
MOCA total score, median (IQR) | 26 (24–27) | 27 (25–29) | 0.21 | 0.13 | −0.41 to 0.67 |