Table 3 Linear Mixed-models for each primary outcome variable GDS-30 assessed at T2, T3, and T4 and PTSS-10 (assessed at T3 and T4). All models included subjects as a random effect and study group (striatal versus non-striatal), time point of assessment, female sex, age, and lesion volume in millilitres (mL)
From: Neuropsychiatric changes following striatal stroke– results from the observational PostPsyDis study
Dependent variable: Geriatric Depression Score | ||||
|---|---|---|---|---|
Fixed-effects | ||||
Coefficient | Std. Error | p-value | 95% CI | |
Time-point of assessment | ||||
T2 (1d | - reference - | - reference - | - | |
T3 (90d) | 0.93 | 0.56 | 0.100 | -0.18–2.0 |
T4 (12mo) | 2.8 | 0.59 | < 0.001 | 1.6–3.9 |
Striatal infarction | 1.5 | 0.87 | 0.089 | -0.2–3.2 |
Lesion volume (mL) | 0.01 | 0.02 | 0.588 | -0.03–0.05 |
Female | 0.57 | 0.87 | 0.509 | -1.1–2.3 |
Age | -0.12 | 0.03 | 0.606 | -0.09–0.05 |
Random-effects | ||||
Estimate | Std. Error | |||
Subject ID | 3.1 | 0.36 | 2.4–3.9 | |
Dependent variable: Post-Traumatic Stress Syndrome 10-Question Inventory | ||||
Fixed-effects | ||||
Coefficient | Std. Error | p-value | 95% CI | |
Time-point of assessment | ||||
T3 (90d) | - reference - | - reference - | - | |
T4 (12mo) | 0.83 | 1.1 | 0.444 | -1.3–2.9 |
Striatal infarction | 1.2 | 1.9 | 0.548 | -2.6–4.9 |
Lesion volume (mL) | 0.03 | 0.04 | 0.476 | -0.05–0.10 |
Female | 4.4 | 1.9 | 0.024 | 0.57–8.2 |
Age | -0.17 | 0.08 | 0.028 | -0.32 - -0.02 |
Random-Effects | ||||
Estimate | Std. Error | 95% CI | ||
Subject ID | 6.8 | 0.84 | 5.5–8.7 | |