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Table 3 Stroke characteristics, EVT safety and efficacy metrics

From: Endovascular treatment in ischemic stroke with active cancer: retrospective analysis of university stroke center data

Items

Overall*

N = 336

Active Cancer*

N = 39

No Cancer*

N = 297

p-value

TOAST Category

   

0.16

 Cardioembolism

181 (54%)

16 (41%)

165 (56%)

 

 Large Artery Atherosclerosis

39 (12%)

4 (10%)

35 (12%)

 

 Unknown Etiology

110 (33%)

19 (49%)

91 (31%)

 

 Other Defined Etiology

6 (1.8%)

0 (0%)

6 (2.0%)

 

Occlusion Site

   

0.42

 Anterior Circulation

299 (89%)

33 (85%)

266 (90%)

 

 Posterior Circulation

35 (10%)

6 (15%)

29 (9.8%)

 

 Both

2 (0.6%)

0 (0%)

2 (0.7%)

 

Bridging IVT

123 (37%)

6 (15%)

117 (39%)

0.004

Successful Recanalization

276 (82%)

32 (82%)

244 (82%)

> 0.99

NIHSS at Admission

13 (8, 18)

14 (7,18)

13 (8,18)

0.78

NIHSS at Discharge

9 (2, 22)

9 (2, 42)

9 (2, 20)

0.49

mRS at Admission

5 (4,5)

5 (4,5)

5 (4,5)

0.98

mRS at Discharge

5 (3,6)

5 (3,6)

5 (3,6)

0.54

Change in NIHSS

-3 (-9,7)

-2 (-8,18)

-3 (-9,6)

0.44

mRS at Admission

   

0.52

 0

1 (0.3%)

0 (0%)

1 (0.3%)

 

 1

5 (1.5%)

1 (2.6%)

4 (1.3%)

 

 2

18 (5.4%)

3 (7.7%)

15 (5.1%)

 

 3

36 (11%)

5 (13%)

31 (10%)

 

 4

89 (26%)

7 (18%)

82 (28%)

 

 5

187 (56%)

23 (59%)

164 (55%)

 

mRS at Discharge

   

0.82

 0

12 (3.6%)

1 (2.6%)

11 (3.7%)

 

 1

49 (15%)

6 (15%)

43 (14%)

 

 2

45 (13%)

5 (13%)

40 (13%)

 

 3

36 (11%)

5 (13%)

31 (10%)

 

 4

45 (13%)

3 (7.7%)

42 (14%)

 

 5

81 (24%)

8 (21%)

73 (25%)

 

 6

68 (20%)

11 (28%)

57 (19%)

 

Change in mRS

0 (-2,1)

0 (-2,1)

0 (-2,1)

0.48

Excellent Outcome (mRS 0–1)

61 (18%)

7 (18%)

54 (18%)

> 0.99

Good Outcome (mRS 0–2)

106 (32%)

12 (31%)

94 (32%)

> 0.99

Mortality

68 (20%)

11 (28%)

57 (19%)

> 0.99

Stroke-Related Mortality

51 (75%)

7 (64%)

44 (77%)

0.45

Peri-interventional Complications

36 (11%)

2 (5.1%)

34 (11%)

0.36

Neurosurgical Intervention

18 (5.4%)

2 (5.1%)

16 (5.4%)

0.70

ICH (all cases)**

85 (25%)

8 (21%)

77 (26%)

0.85

Hemorrhagic Transformation

31 (36%)

4 (50%)

27 (36%)

0.48

Intraparenchymal hemorrhage within and beyond infarct with mass effect

15 (18%)

0 (0%)

15 (20%)

0.66

Other Types of ICH

53 (63%)

4 (50%)

49 (64%)

0.48

Symptomatic ICH

19 (23%)

0 (0%)

19 (25%)

0.34

  1. *n (%); Median (IQR). ** Some patients were allocated to two categories, for example when both hemorrhagic transformation and subarachnoid bleeding occurred. Abbreviations: ICH: intracranial hemorrhage, IVT: intravenous thrombolysis, mRS: modified Rankin Scale, NIHSS: National Institute of Health Stroke Scale, TOAST: Trial of Org 10,172 in Acute Stroke Treatment